Novel bisheterocycles 4-6 have been synthesized by green approach using cheaper, reusable, non toxic magnetically separable MgFe₂O₄ as nano catalyst. Bis chalcone and binucleophiles were treated on MgFe₂O₄ heterogenous catalyst in refluxing ethanol to afford the novel bis heterocycles 4-6 in very good yields with very less reaction time. The newly synthesized compounds were characterized by NMR (¹H & ¹³C), FTIR and mass spectroscopy, thereafter evaluated for their antibacterial activities against Bacillus subtilis (MTCC No.121), Escherichia coli (MTCC No.118), Staphylococcus aureus (MTCC No. 96) and Salmonella typhi (MTCC No. 98) while antifungal activities were tested against Aspergillus niger (MTCC No. 281) and Candida albicans  (MTCC No. 2479) using disc diffusion method. The reported novel compounds exhibited a good range of antimicrobial activities, opening plethora of oppournities in the field of research in antibiotics.