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Synthesis and reactivity of new heterocyclic systems derived from 5-chloro-1H-indole-2,3-dione


 
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1. Title Title of document Synthesis and reactivity of new heterocyclic systems derived from 5-chloro-1H-indole-2,3-dione
 
2. Creator Author's name, affiliation, country Z. Tribak
 
2. Creator Author's name, affiliation, country A. Haoudi
 
2. Creator Author's name, affiliation, country Y. Kandri Rodi
 
2. Creator Author's name, affiliation, country H. Elmsellem; Laboratoire de chimie analytique appliquée, matériaux et environnement (LC2AME), Faculté des Sciences, B.P. 717, 60000 Oujda, Morocco
 
2. Creator Author's name, affiliation, country M. K. Skalli
 
2. Creator Author's name, affiliation, country Y. Ouzidan
 
2. Creator Author's name, affiliation, country A. Mazzah
 
2. Creator Author's name, affiliation, country E.M. Essassi
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) 5-Chloro-1H indole-2,3-dione; PTC; synthesis; N-alkylation; derivatives
 
4. Description Abstract

In this article, we described the synthesis of various derivatives of 5-Chloroisatin by the action of halogenated mono channels, benzyl chloride and methyl iodide under the conditions of phase transfer catalysis (PTC), which are widely used as a starting material for the synthesis of heterocyclic compounds and as substrates for the synthesis of drugs.

In order to multiply the family heterocyclic compound from 5-Chloro-1H-indole-2,3-dione using the N-alkylation reaction which is answered in the field of organic chemistry and on which several studies were performed. The various products were determined by 1H NMR, and 13C NMR spectroscopy with good yield.

 
5. Publisher Organizing agency, location
 
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7. Date (YYYY-MM-DD) 20-01-2017
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/morjchem/article/view/7662
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48317/IMIST.PRSM/morjchem-v4i4.7662
 
11. Source Title; vol., no. (year) Moroccan Journal of Chemistry; Vol 4, No 4 (2016)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c)