Synthesis and Biological Activities of a Novel Naringin based Heterocyclic Derivatives
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Synthesis and Biological Activities of a Novel Naringin based Heterocyclic Derivatives |
| 2. | Creator | Author's name, affiliation, country | Shehdeh Jodeh; Palestinian Territory, Occupied |
| 2. | Creator | Author's name, affiliation, country | Nuha Shawarb; Department of Chemistry, An-Najah National University, Nablus, Palestine.; Palestinian Territory, Occupied |
| 2. | Creator | Author's name, affiliation, country | Nidal Jaradat; Department of Chemistry, An-Najah National University, Nablus, Palestine.; Palestinian Territory, Occupied |
| 2. | Creator | Author's name, affiliation, country | Ismail Warad; Department of Chemistry, An-Najah National University, Nablus, Palestine.; Palestinian Territory, Occupied |
| 2. | Creator | Author's name, affiliation, country | Fatima Hussein; Department of Chemistry, An-Najah National University, Nablus, Palestine.; Palestinian Territory, Occupied |
| 2. | Creator | Author's name, affiliation, country | Moutasim El-Masri; Department of Chemistry, An-Najah National University, Nablus, Palestine.; Palestinian Territory, Occupied |
| 2. | Creator | Author's name, affiliation, country | Rachid Salghi; Laboratory of Environmental Engineering and Biotechnology, ENSA, Ibn Zohr University, PO Box 1136, 80000 Agadir, Morocco; Morocco |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | antibacterial activity, antioxidant, naringin; dioxolan, imidazolidin |
| 4. | Description | Abstract | A number of naringin based heterocyclic derivatives dioxolane and imidazolidine have been synthesized and evaluated for their antioxidant and biological activities. The chemical structures of the newly synthesized compounds were verified on the basis of spectral and elemental methods of analysis. Investigation of antibacterial activity of these compounds was determined by measuring MIC value using broth micro dilution method for Gram-positive and Gram-negative bacteria, among the various synthesized compounds. Dioxolane showed the highest antibacterial activity with minimal inhibitory concentration (MIC) of 0.125mg/ml, in addition this compound exhibit the best antioxidant activity with inhibition concentration (IC50) of 18.7 μg/mL, compared with other semi synthetic derivative. |
| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (YYYY-MM-DD) | 19-01-2016 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://revues.imist.ma/index.php/morjchem/article/view/4254 |
| 10. | Identifier | Digital Object Identifier (DOI) | https://doi.org/10.48317/IMIST.PRSM/morjchem-v4i1.4254 |
| 11. | Source | Title; vol., no. (year) | Moroccan Journal of Chemistry; Vol 4, No 1 (2016) |
| 12. | Language | English=en | en |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
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