Synthesis, identification, thermal analysis, computational, and antibacterial studies of Z-N'-(5-bromothiophen-2-yl)methylene)nicotinohydrazide
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| 1. | Title | Title of document | Synthesis, identification, thermal analysis, computational, and antibacterial studies of Z-N'-(5-bromothiophen-2-yl)methylene)nicotinohydrazide |
| 2. | Creator | Author's name, affiliation, country | Yahya Hussam |
| 2. | Creator | Author's name, affiliation, country | Ahmad Abu-Obaid |
| 2. | Creator | Author's name, affiliation, country | Ashraf Sawafta |
| 2. | Creator | Author's name, affiliation, country | Dyala Abu-Aladel |
| 2. | Creator | Author's name, affiliation, country | I. Asadi Ahmad |
| 2. | Creator | Author's name, affiliation, country | Rami Shariah |
| 2. | Creator | Author's name, affiliation, country | Tasneem Alayed |
| 2. | Creator | Author's name, affiliation, country | Ismail Warad; (a)Department of Chemistry, Science College, An-Najah National University, P.O. Box 7, Nablus, Palestine (b) Biology and Biotechnology Department, An-Najah National University, P.O. Box 7, Nablus, Palestine (c)Department of Basic Science, Faculty of Engineering, Applied Science Private University, PO Box 166, Amman 11931, Jordan *corresponding authosr; E-Mail: obaid@najah.edu and warad@najah.edu Tel./Fax: +970-9234-5982.; Saudi Arabia |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | FT-IR, condensation, TG, Schiff bases, DFT. |
| 4. | Description | Abstract | N'-((5-bromothiophen-2-yl)methylene)nicotinohydrazide Schiff base was isolated and characterized as Z-isomer. Ethanoic reflux condensation of equivalent amount of nicotinohydrazideand with 5-bromothiophene-2-carbaldehyde produced the desired compound in good yield. The condensation reaction was monitored by FT-IR and UV-visible as well as DFT calculation. The structure of desired compound wasexperimentally analyzed based on: elemental analysis, EI-Ms, UV-visible, FT-IR spectral, TG/DTG and 1H-NMR.DFT-computational calculation supportedZ- isomer as favorited product over E one, good accordance between experimental and theoretical calculated were recorded. The antibacterial results obtained using the desired compound indicates a promising result against human pathogenic bacteria.
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| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (YYYY-MM-DD) | 20-01-2016 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://revues.imist.ma/index.php/morjchem/article/view/4183 |
| 10. | Identifier | Digital Object Identifier (DOI) | https://doi.org/10.48317/IMIST.PRSM/morjchem-v4i1.4183 |
| 11. | Source | Title; vol., no. (year) | Moroccan Journal of Chemistry; Vol 4, No 1 (2016) |
| 12. | Language | English=en | en |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
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