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Indonesia Herbal Medicine and Its Active Compounds for Anti-diabetic Treatment: A Systematic Mini Review


 
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1. Title Title of document Indonesia Herbal Medicine and Its Active Compounds for Anti-diabetic Treatment: A Systematic Mini Review
 
2. Creator Author's name, affiliation, country N. N. Fajriyah; Department of Nurse, Muhammadiyah Pekajangan Pekalongan University, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country E. Mugiyanto; Department of Pharmacy, Muhammadiyah Pekajangan Pekalongan University, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country K. S. Rahmasari; Department of Pharmacy, Muhammadiyah Pekajangan Pekalongan University, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country A. V. Nur; Department of Pharmacy, Muhammadiyah Pekajangan Pekalongan University, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country V. H. Najihah; Medicinal Chemistry Research Group, HAMNOX Research Center, Kademangan, Setu, 15313, Tangerang Selatan, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country Muh. N. K. Wihadi; Research Center for Chemistry, National Research and Innovation Agency (BRIN), Republik Indonesia, Kawasan Sains dan Teknologi (KST) B. J. Habibie, Tangerang Selatan 15311, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country M. Merzouki; Morocco
 
2. Creator Author's name, affiliation, country A. Challioui; Morocco
 
2. Creator Author's name, affiliation, country T-H. Vo; School of Medicine, Vietnam National University Ho Chi Minh City, Ho Chi Minh City 700000, Vietnam; Viet Nam
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Anti-diabetic; Herbal remedies; Medicine; Natural compounds; Indonesia
 
4. Description Abstract We reported the systematic review of anti-diabetic herbal medicine from Indonesia by integrating herbal medicine databases and summarized the anti-diabetic compounds in Indonesian plants. We used data sources from Pubmed and local Indonesian databases such as Portal Garuda and Basis Data Tanaman Obat Indonesia (BDTOI) to elucidate anti-diabetic candidate herbal medicine. We found 927 articles (PubMed) and 70 articles (Portal Garuda) based on the criteria of anti-diabetic properties. After thoroughly assessing those publications, 38 articles on controlling blood glucose were identified. Moreover, we utilized ClinicalTrial.gov to map the evidence. Five species (Abelmoschus esculentus, Allium sativum L, Cinnamomum cassia, Citrullus colocynthis, and Punica granatum L) passed the clinical trial, three of which were intended for use in treating other diseases, and eight of which lacked clinical evidence. Additionally, over 30 compounds were elucidating from those herbs, including quercetin and allicin. In conclusion, we successfully retrieved anti-diabetic herbal medicine from Indonesia by integrating public databases. The molecular docking study was employed to predict and optimize the anti-diabetic outcomes.
 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s) National Research and Innovation Agency Republic of Indonesia
 
7. Date (YYYY-MM-DD) 01-08-2023
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/morjchem/article/view/40481
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48317/IMIST.PRSM/morjchem-v11i04.40481
 
11. Source Title; vol., no. (year) Moroccan Journal of Chemistry; Vol 11, No 04 (2023): pp. 897-1318
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2023 Moroccan Journal of Chemistry