Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases |
| 2. | Creator | Author's name, affiliation, country | N. A. Samad Selman; Iraq |
| 2. | Creator | Author's name, affiliation, country | L. J. Abbas; Department of pharmaceutical chemistry, College of Pharmacy, University of Basrah, Iraq; Iraq |
| 2. | Creator | Author's name, affiliation, country | A. S. Abdullah; Department of Pharmacology and Toxicology, College of Pharmacy, University of Basrah, Iraq; Iraq |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | Steroidal derivatives, Cholesterol, Ergosterol, Anti-inflammatory, Antioxidant, Schiff bases |
| 4. | Description | Abstract | In the present work, two aldehyde derivatives were synthesized one from cholesterol and one from ergosterol and further condensed with three different primary amines (2-amino 6-fluoro benzathiazole, thiosemicarbazide, carbohydrazide) to yield the corresponding Schiff’s bases. The synthesized compounds were verified using spectral analysis, including IR, 1H-NMR, and GC Mass, and were tested for antioxidant and anti-inflammatory properties. From the synthetic materials, three to four compounds showed significant anti-inflammatory and antioxidant activities.
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| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (YYYY-MM-DD) | 01-08-2023 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://revues.imist.ma/index.php/morjchem/article/view/40231 |
| 10. | Identifier | Digital Object Identifier (DOI) | https://doi.org/10.48317/IMIST.PRSM/morjchem-v11i04.40231 |
| 11. | Source | Title; vol., no. (year) | Moroccan Journal of Chemistry; Vol 11, No 04 (2023): pp. 897-1318 |
| 12. | Language | English=en | en |
| 13. | Relation | Supp. Files |
HNMR^MIR^MGC mass documents (B) HNMR^MIR^MGC mass documents (5MB) Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases (596KB) Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases (597KB) Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases (660KB) Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases (663KB) Anti-inflammatory and Antioxidant Activity Screening for New Steroidal Schiff Bases (693KB) |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
Copyright (c) 2023 Moroccan Journal of Chemistry |