Sulfur Nanoparticle as an Effective HEK-293 Anticancer Agent
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Sulfur Nanoparticle as an Effective HEK-293 Anticancer Agent |
| 2. | Creator | Author's name, affiliation, country | M. Suleiman |
| 2. | Creator | Author's name, affiliation, country | A. Alali |
| 2. | Creator | Author's name, affiliation, country | N. Aljayyousi |
| 2. | Creator | Author's name, affiliation, country | K. Alkanad |
| 2. | Creator | Author's name, affiliation, country | N. El-khatatneh |
| 2. | Creator | Author's name, affiliation, country | M. Almaqashah |
| 2. | Creator | Author's name, affiliation, country | A. Zarrouk |
| 2. | Creator | Author's name, affiliation, country | A. Abu-Rayyan |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | S-NPs; UV-vis.; cytotoxicity; anticancer activity |
| 4. | Description | Abstract | The preparation of sulfur nanoparticles (S-NPs) by a fast precipitation low-temperature approach using hydrochloric acid, sodium thiosulfate, and tetrabutylammonium bromide (TOAB) as a surfactant and stabilized has been reported in this work. The atomic content and purity of the S-NPs were supported by Energy Dispersive X-ray (EDX), and scanning electron microscopy (SEM) imaging supported the morphology and demonstrated nanoparticle aggregation. The progress of S-NPs preparation was monitored via UV-vis and optical activities behavior. The structure and the size of S-NPs were examined via powder X-Ray diffraction (PXRD) analysis. Transmission electron microscope (TEM) conforms the prepared S-NPs are in homogenous nano-sized with a value of 7-10 nm. The thermal stability of the desired S-NPs matrix was also determined by TG/DTG measurements. S-NPs' in vitro cytotoxic activities were evaluated against the HL-60 acute myeloid leukemia cell line, the HEK-293 kidney carcinoma cell line, and the HT-29 colon cancer cell line. The cytotoxicity of HEK-293 cell lines treated with S-NPs was higher than that of the other cell lines, according to the MTT assay. |
| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | An-najah university |
| 7. | Date | (YYYY-MM-DD) | 24-02-2023 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://revues.imist.ma/index.php/morjchem/article/view/37722 |
| 10. | Identifier | Digital Object Identifier (DOI) | https://doi.org/10.48317/IMIST.PRSM/morjchem-v11i2.37722 |
| 11. | Source | Title; vol., no. (year) | Moroccan Journal of Chemistry; Vol 11, No 2 (2023) |
| 12. | Language | English=en | en |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
Copyright (c) 2023 Moroccan Journal of Chemistry |