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Eenhanced electrochemical sensing of Nimodipine with Sodium montmorillonite clay


 
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1. Title Title of document Eenhanced electrochemical sensing of Nimodipine with Sodium montmorillonite clay
 
2. Creator Author's name, affiliation, country M. Sikkander; VELAMMAL ENGINEERING COLLEGE; India
 
2. Creator Author's name, affiliation, country C. Vedhi; Department of Chemistry, V.O Chidambaram College, Tuticorin-628008, Tamil Nadu, India; India
 
2. Creator Author's name, affiliation, country P. Manisankar; Department of Industrial Chemistry, Alagappa University, Karaikudi-630003, Tamil Nadu, India; India
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Nimodipine, Electrochemical, sodium montmorillonite,DPSV,Peak Potential
 
4. Description Abstract

Nano size surface of sodium montmorillonite was prepared via a colloidal physical approach and deposited onto glassy carbon electrodes and used as working electrode. A highly sensitive electrochemical biosensor for the detection of trace amount of calcium channel blocking drug has been designed. The cyclic voltametric behaviour of the drug was studied in media with five ranges of pH. Among the pHs studied, pH 13.0 showed good response for the drug. Differential pulse stripping voltammetry was employed and the optimum condition was arrived at. Accumulation of the substrate was ascertained from SEM analysis. A simple, sensitive and time-saving differential pulse stripping voltammetric procedure has been developed for determination of antihypertensive drug in its commercial tablet. The method was successfully applied to the determination of the drug in tablets and proved to be reliable.

 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 30-09-2014
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/morjchem/article/view/2135
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48317/IMIST.PRSM/morjchem-v2i4.2135
 
11. Source Title; vol., no. (year) Moroccan Journal of Chemistry; Vol 2, No 4 (2014)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c)