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Investigation of antioxidant activity of some bis-benzimidazole in Tetrahymena thermophila stressed cells


 
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1. Title Title of document Investigation of antioxidant activity of some bis-benzimidazole in Tetrahymena thermophila stressed cells
 
2. Creator Author's name, affiliation, country Amine OUAKET; Biomolecules and Organic Synthesis Laboratory, Center of Health and Biomolecules, Faculty of Sciences Ben M’sik, University Hassan II of Casablanca, Morocco.; Morocco
 
2. Creator Author's name, affiliation, country Boutaina ADDOUM; Physiopathology, Genetics, Molecular and Biotechnology Laboratory, Center of Health and Biomolecules, Faculty of Sciences Ain Chock, University Hassan II of Casablanca, Morocco.; Morocco
 
2. Creator Author's name, affiliation, country Bouchra EL KHALFI; Physiopathology, Genetics, Molecular and Biotechnology Laboratory, Center of Health and Biomolecules, Faculty of Sciences Ain Chock, University Hassan II of Casablanca, Morocco.; Morocco
 
2. Creator Author's name, affiliation, country Abdelaziz SOUKRI; Physiopathology, Genetics, Molecular and Biotechnology Laboratory, Center of Health and Biomolecules, Faculty of Sciences Ain Chock, University Hassan II of Casablanca, Morocco.; Morocco
 
2. Creator Author's name, affiliation, country Noureddine KNOUZI; Biomolecules and Organic Synthesis Laboratory, Center of Health and Biomolecules, Faculty of Sciences Ben M’sik, University Hassan II of Casablanca, Morocco.; Morocco
 
2. Creator Author's name, affiliation, country Mohamed BERRADA; Biomolecules and Organic Synthesis Laboratory, Center of Health and Biomolecules, Faculty of Sciences Ben M’sik, University Hassan II of Casablanca, Morocco.; Morocco
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Bis-benzimidazole; Antioxidant activity; Toxicity; Cell; Tetrahymena; Stress
 
4. Description Abstract

In this paper, we present experimental findings on the protective effect of some bis-benzimidazole molecules against oxidative (H2O2) and nitrosative (SNP) stress using the protozoan T. thermophila as a cellular model. The results of this article show that the molecules 2,2’-Benzendiyl-1,4-Bis-(5-amino-1H-benzimidazole) and 2,2’-Octandiyl-1,8-Bis-(quinolin-8-ol-5-azo-1H-benzimidazole) have a protective effect against stress important than the molecule 2,2’-Benzendiyl-1,4-Bis-(1H-benzimidazole).

 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s) CNRST
 
7. Date (YYYY-MM-DD) 14-02-2021
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/morjchem/article/view/20868
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48317/IMIST.PRSM/morjchem-v9i2.20868
 
11. Source Title; vol., no. (year) Moroccan Journal of Chemistry; Vol 9, No 2 (2021)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2021 Moroccan Journal of Chemistry