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Assessment of the Chemical/biological activities of extracts and essential oil of Rosmarinus officinalis L. from the Oriental region of Morocco


 
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1. Title Title of document Assessment of the Chemical/biological activities of extracts and essential oil of Rosmarinus officinalis L. from the Oriental region of Morocco
 
2. Creator Author's name, affiliation, country Ab. Oussaid; Laboratory of molecular chemistry, Matérials et Environment, Multidisciplinary Faculty of Nador, B.P. 300, Selouane, Nador 62700, Mohammed first University Oujda, Maroc.; Morocco
 
2. Creator Author's name, affiliation, country M. Azzouzi; Laboratory of molecular chemistry, Matérials et Environment, Multidisciplinary Faculty of Nador, B.P. 300, Selouane, Nador 62700, Mohammed first University Oujda, Maroc.; Morocco
 
2. Creator Author's name, affiliation, country A. Ibn Mansour; Laboratory of applied organic chemistry, Faculty of Sciences of Tétouan, Abdelmalek Essaadi University, Morocco.; Morocco
 
2. Creator Author's name, affiliation, country M. Azouagh; Laboratory of molecular chemistry, Matérials et Environment, Multidisciplinary Faculty of Nador, B.P. 300, Selouane, Nador 62700, Mohammed first University Oujda, Maroc.; Morocco
 
2. Creator Author's name, affiliation, country M. Koudad; Laboratory of molecular chemistry, Matérials et Environment, Multidisciplinary Faculty of Nador, B.P. 300, Selouane, Nador 62700, Mohammed first University Oujda, Maroc.; Morocco
 
2. Creator Author's name, affiliation, country A. Oussaid; Laboratory of molecular chemistry, Matérials et Environment, Multidisciplinary Faculty of Nador, B.P. 300, Selouane, Nador 62700, Mohammed first University Oujda, Maroc.; Morocco
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) : Essential oil; Gas chromatography; Phytochemical screening; Antioxidant activity; antimicrobial activity; Rosmarinus officinalis L.
 
4. Description Abstract

The interest in natural conservatives, antimicrobial and antioxidants have slightly increased due to their advantageous effects. In this work bioactive compounds were obtained from Rosmarinus officinalis L. At first, the extractions of the essential oils by hydrodistillation was performed. The obtained essential oils from rosemary were yielded of about 1.8%. The GC-MS revealed that the rosemary oil was dominated by 1,8-cinéol (52.440 %), Camphor (11.241 %), and α-pinene (8.225%). The extraction of the dry powders using maceration and soxhlet with solvents of different polarity showed a significant yield for ethanol compared to that of hexane.

In the same context, the phytochemical screening revealed the richness of the studied plant with secondary metabolites. The antioxidant activity was assessed in vitro using scavenging activity of the free radical DPPH. It revealed that the essential oil and all ethanolic extracts tested using ascorbic acid as a reference, exhibit anti-radical activities. The ethanolic extract of Rosemary leaves showed the highest anti-radical activity (IC50 = 64.27µg/ml), followed by the extract of the latter's stems with an IC50 = 64.74µg/ml. The microbiological results showed that the antimicrobial activity was variable from one bacteria to another, this is due to the variability of the chemical composition of each extract.
 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s) No Contributors or Supporting Agencies
 
7. Date (YYYY-MM-DD) 02-07-2020
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/morjchem/article/view/20151
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48317/IMIST.PRSM/morjchem-v8i3.20151
 
11. Source Title; vol., no. (year) Moroccan Journal of Chemistry; Vol 8, No 3 (2020)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2020 Moroccan Journal of Chemistry