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In Morocco, the industrial revolution and agricultural activities are contributing to the increase of water pollution, leading to possibility to the appearance of serious diseases of endocrine origin. 

The objective of this study is to focus on the impact of industrial pollution in the Dokkarat district of the Fez city on the appearance of some endocrine diseases in the adjacent population and equally important on the waters upstream from Oued Fez. The results of the diagnosis show that the Dokkarat district includes several modern tanneries and other food industries that use chemicals identified as toxically. The physicochemical and bacteriological characterization of Oued Fez water downstream from the industries diagnosed, displays that they are slightly basic, carring a high bacterial load, a mineral and organic load in the surface water quality standards, a metallic charge at the limit of the standards with the exception of arsenic. The statistical analysis of the survey data recorded the presence of six endocrine diseases (diabetes, neurological disorders, hormonal imbalance, obesity, thyroid and growth disorders) and a strong correlation between age, years of experience, length of exposure and occurrence of endocrine pathological signs.