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Comparative evaluation of total phenolic content, total flavonoids content and antioxidants activity in Skin & Pulp extracts of Cucurbita maxima


 
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1. Title Title of document Comparative evaluation of total phenolic content, total flavonoids content and antioxidants activity in Skin & Pulp extracts of Cucurbita maxima
 
2. Creator Author's name, affiliation, country souad Rakass; Taibah University Madina, Saudi Arabia; Saudi Arabia
 
2. Creator Author's name, affiliation, country Hind A. A. Babiker; (a)Taibah University, College of science, Chemistry Department, Almadinah 30002 Saudi Arabia (b)Al-Neelain University, Faculty of Science, Biochemistry and Molecular Biology Department, Sudan; Saudi Arabia
 
2. Creator Author's name, affiliation, country Hicham Oudghiri-Hassani; (a)Taibah University, College of science, Chemistry Department, Almadinah 30002 Saudi Arabia (b)Cégep de Drummondville, 960 rue Saint-Georges, Drummondville (Québec) J2C 6A2 Canada
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Phenolic content, flavonoids content, antioxidants activity, Skin, Pulp, extracts Cucurbita maxima
 
4. Description Abstract The aim of this study was to determine the total phenolic content, total flavonoids content, and antioxidant activity of various extracts of pumpkin Cucurbita maxima skin and pulp. The various solvents used for extraction were acetone, methanol, ethanol and water. The total phenolic content in pulp extracts ranged from 9.72 ± 0.37 to 106.92 ±0.47 mg GAE/g of extract, while in skin extracts ranged from 55.91 ± 5.67 to 336.19 ± 0.89 mg GAE/g of extract. The total flavonoids content varied from 0.13 ± 0.01 to 2.21 ±0.06 mg CE/g of extract in pulp extracts and from 1.17 ± 0.08 to 4.64 ± 0.02 mg CE/g of extract in skin extracts. Antioxidant activity of extracts was expressed as percentage of 2, 2-diphenyl-1-picrylhydrazyl (DPPH), IC50 values (mg/ml), and radicals inhibition. The IC50 values in pulp ranged from 1.55 to 4.01 mg /ml and from 1.12 to 67.64 mg/ml in skin. The highest antioxidant scavenging activity was obtained in water skin extract (lowest IC50 value of 1.12 mg/ml). The Cucurbita maxima skin extracts contains impressively higher total phenolic and total flavonoids contents when compared to pulp extracts. The present study revealed that the skin followed by the pulp of pumpkin Cucurbita maxima could be used as an excellent natural source of antioxidant.
 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 03-02-2018
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/morjchem/article/view/11310
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48317/IMIST.PRSM/morjchem-v6i2.11310
 
11. Source Title; vol., no. (year) Moroccan Journal of Chemistry; Vol 6, No 2 (2018)
 
12. Language English=en en
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2018 Moroccan Journal of Chemistry