SYNTHESIS OF NEW 5-BROMO-1H-INDOLE-2,3-DIONE DERIVATIVES BY 1,3-DIPOLAR CYCLOADDITION

Y. Kharbach, Kandri Rodi Youssef, H. Elmsellem, A. Haoudi, M.K. Skalli, Y. Ouzidan, M. Akhazzane, A. Mazzah, E.M. Essassi

Abstract


To contribute to the development of the chemistry of 5-bromo-isatin, we have synthesized new heterocyclic systems, using alkylation reactions under conditions of phase transfer catalysis to be then subjected to cycloaddition reactions dipolar involving 1,3-dipoles.

The structures of the various products obtained were determined by 1H NMR, 13C NMR spectroscopy.


Keywords


5-bromoisatin ; 1,3-dipolar cycloaddition ; dipolarophile ; heterocyclic.

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DOI: https://doi.org/10.48317/IMIST.PRSM/morjchem-v5i1.7960