Facile Synthesis of Mono and Bisfurazanopiperazines

Abstract

A simple and convenient synthesis of monofurazanopiperazine (4,5,6,7-tetrahydro[1,2,5]oxadiazolo[3,4-b]pyrazine) and bisfurazanopiperazine (4H,8H-bis[1,2,5]oxadiazolo[3,4-b;3¢,4¢-e]pyrazine) was achieved in excellent yields. Diaminofurazan was synthesized by the cyclocondensation of diaminoglyoxime under solvent-free condition and further used in the synthesis of both the compounds.