Mini Review on synthetic methods and biological activities of various substituted pyrimidine derivatives

Abstract

Pyrimidines are versatile nitrogen containing heterocyclic compounds, possessing various types of biological and pharmacological activities like antimicrobial, hypotensive, antimalerial, antidepressant, antitubercular, anticoagulant, hypnotic, fungicidal, anti-inflammatory, analgesic, antiulcer, antiviral and anticancer and other useful activities. Pyrimidine nucleus is endowed with a variety of therapeutic activities and new Pyrimidine are known to be biologically active compounds possessing several pharmacological activities

Pyrimidines aroused our interest in synthesizing new Pyrimidines nucleus featuring different substitution with more potent pharmacologically active compounds.