Cyclization of some N-Arylidene-2-(Acetamido)-3-(4-Chlorophenyl)Acrylohydrazides to 1-Arylideneamino-4-(4-Chlorobenzylidene)-2-Methyl-1h-Imidazolin-5(4h)-Ones

Abstract

Cyclization of the N-arylidene-2-(acetamido)-3-(4-chlorophenyl)acrylohydrazides, which were prepared from 4-chlorobenzaldehyde and acetylglycine via 4-chlorobenzylidene-2-methyl-(4H)-oxazol-5-one and then 2-(acetamido)-3-(4-chlorophenyl)acrylohydrazide, on treatment with acetic anhydride gave seven corresponding compounds namely 1-arylideneamino-4-(4-chlorobenzylidene)-2-methyl-1H-imidazolin-5(4H)-ones but did not give 3-acetyl-2-aryl-5-[1-acetamido-2-(4-chlorophenyl)vinyl]-1,3,4-oxadiazolines. The structure of the imidazoline-5-one compounds was confirmed by IR, ¹H-NMR and MS spectral data.