Synthesis and Characterization of Molecularly Imprinted Polymer as Adsorbent for D-arabinitol

Abstract

D-arabinitol is a metabolite product typically of several Candida species that are pathogenic and potentially used for candidiasis markers. In this study, a molecularly imprinted polymers (MIPs) of D-arabinitol has been synthesized and functions as D-arabinitol adsorbent. MIPs will functioned as an adsorbent after removing the template. The resulting polymers was characterized by FTIR, LC-MS and its binding efficiency tested with a batch binding assay. The results of FTIR analysis showed that the MIPs produced contained both monomers and templates. The template removal process was successful enough to see a significant reduction in the D-arabinitol area (no template detected) with LC-MS. The results of the batch binding assay indicated that MIPs has a binding capacity value (Q) of 1.075 mg/g whereas NIPs has a value (Q) of 0.131 mg/g. The results showed that the MIPs produced was potentially used as an adsorbent of D-arabinitol.