Michael-Type Amine Adducts of α-Methylene-γ-Lactones tomentosin

M. Zaki, A. Oukhrib, M-A. Hiebel, S. Berteina-Raboin, M. Akssira

Abstract


In the present study, novel amino lactone derivatives of tomentosin 2 were efficiently prepared through a diastereoselective conjugate addition of several secondary amines to the α-methylene-γ-butyrolactone function of tomentosin 1, a sesquiterpene lactone extracted from Dittrichia viscosa. These compounds were fully characterized by spectroscopic methods.


Keywords


Tomentosin; Dittrichia Viscosa; Michael addition; Amino-tomentosin

Full Text:

PDF


DOI: https://doi.org/10.48317/IMIST.PRSM/morjchem-v7i3.14007