A review of Group B Streptococcus maternal-fetal infection

Hanane BEN-TALEB, Kaotar NAYEME, Halima LEBRAZI, Mostafa CHAMEKH, Rachid SAILE, Khalid ZEROUALI, Mohammed TIMINOUNI

Abstract


For a long time, infectious diseases have been a major public health problem, mainly maternal fetal infections linked to neonate’s mortality. Streptococcus agalactiae (GBS) infection is one of the main infections, which threat mother-infant health. One of the major challenges that remains to be addressed is therapeutic care strategy, further, the emergence of antibiotic resistant bacteria which constitute a major challenge for clinicians. Concerning GBS an antibiotic prophylaxis regimen is adopted to reduce the vertical transmission of bacteria from mother to neonate and avoid the appearance of complications related to GBS infection such as early onset disease and late onset disease that can lead to stillbirths. Like most bacteria, GBS is susceptible to first-line antibiotics, and in case of resistance, therapy is based on second and third-line antibiotics. The drug susceptibility testing of microorganisms is therefore essential in the therapeutic strategy, because it not only facilitates the orientation of treatment but also help to set up a system supervising the expansion of resistant strains. This present paper constitutes a literature review on Streptococcus agalactiae maternal-fetal infection and summarizes some epidemiological studies on the emergence of this bacterium as well as it provides the prevalence of its resistance to antibiotics and outlines some vaccine development strategies.


Keywords


Streptococcus agalactiae; GBS; infection; epidemiology; antibiotic resistance; vaccine.

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References


• Ait, A.A., Hamidechi, M.A. (2003) “Incidence du streptocoque du groupe b (SGB) chez les nouveau-nés nés à Constantine (Algérie) et dans deux de ses banlieues. Intérêt de la détermination des sérotypes’’ Médecine Mal. Infect. 33, 417–421. https://doi.org/10.1016/S0399-077X(03)00222-1

• Lu B, Chen X, Wang J, Wang D, Zeng J, Li Y, Li D, Zhu F, Cui Y, Huang L. (2016) “Molecular characteristics and antimicrobial resistance in invasive and noninvasive Group B Streptococcus between 2008 and 2015 in China’’ Diagn Microbiol Infect Dis. 2016 Dec;86(4):351-357. doi: 10.1016/j.diagmicrobio.2016.08.023. Epub 2016 Aug 28. PMID: 27692802.

• Bassir, A., Dhibou, H., Farah, M., Mohamed, L., Amal, A., Nabila, S., Abderahim, A., Asmouki, H., Soummani, A. (2016) “Portage vaginal du streptocoque du groupe B chez la femme enceinte au niveau de la région de Marrakech [Vaginal colonization by group B streptococcus among pregnant women in the region of Marrakech]’’ The Pan Afr. Med. J. 23, 107. https://doi.org/10.11604/pamj.2016.23.107.9047

• Ben Hamida Nouaili, E., Abidi, K., Chaouachi, S., Marrakchi, Z. (2011) “Épidémiologie des infections materno-fœtales à streptocoque du groupe B’’ Médecine Mal. Infect. 41, 123–125. https://doi.org/10.1016/j.medmal.2010.09.004

• Carreras-Abad, C., Ramkhelawon, L., Heath, P.T., Le Doare, K. (2020) “A Vaccine Against Group B Streptococcus: Recent Advances’’ Infect. Drug Resist. 13, 1263–1272. https://doi.org/10.2147/IDR.S203454

• Cassini, A., Högberg, L. D., Plachouras, D., Quattrocchi, A., Hoxha, A., Simonsen, G. S., Colomb-Cotinat, M., Kretzschmar, M. E., Devleesschauwer, B., Cecchini, M., Ouakrim, D. A., Oliveira, T. C., Struelens, M. J., Suetens, C., Monnet, D. L., & Burden of AMR Collaborative Group (2019) “Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis’’ The Lancet. Infectious diseases, 19(1), 56–66. https://doi.org/10.1016/S1473-3099(18)30605-4

• Centers for Disease Control and Prevention. (2021) “Preventing Group B Strep Disease in Newborns’’ https://www.cdc.gov/groupbstrep/about/prevention.html (accessed 1.6.22).

• Cieslewicz, M.J. et al. (2005) “Structural and Genetic Diversity of Group B Streptococcus Capsular Polysaccharides’’ Infection and Immunity, 73(5), pp. 3096–3103. doi:10.1128/IAI.73.5.3096-3103.2005.

• Edwards, M.S., Baker, C.J. (2005) “Group B streptococcal infections in elderly adults’’ Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am. 41, 839–847. https://doi.org/10.1086/432804

Facklam, R. (2002) “What Happened to the Streptococci: Overview of Taxonomic and Nomenclature Changes’’ Clin. Microbiol. Rev. 15, 613–630. https://doi.org/10.1128/CMR.15.4.613-630.2002

• Furfaro, L. L., Chang, B. J., & Payne, M. S. (2018) “Perinatal Streptococcus agalactiae Epidemiology and Surveillance Targets’’ Clinical microbiology reviews, 31(4), e00049-18. https://doi.org/10.1128/CMR.00049-18

• Hanna, M. and Noor, A. (2021) “Streptococcus Group B’’, in StatPearls. Treasure Island (FL): StatPearls Publishing’’ Available at: http://www.ncbi.nlm.nih.gov/books/NBK553143/ (Accessed: 25 December 2021).

• Hayes, K., O’Halloran, F., Cotter, L. (2020) “A review of antibiotic resistance in Group B Streptococcus: the story so far’’ Crit. Rev. Microbiol. 46, 253–269. https://doi.org/10.1080/1040841X.2020.1758626

• Hays, C., Louis, M., Plainvert, C., Dmytruk, N., Touak, G., Trieu-Cuot, P., Poyart, C., Tazi, A. (2016) “Changing Epidemiology of Group B Streptococcus Susceptibility to Fluoroquinolones and Aminoglycosides in France’’ Antimicrob. Agents Chemother. 60, 7424–7430. https://doi.org/10.1128/AAC.01374-16

• Jerbi, M., Hidar, S., Hannachi, N., El Moueddeb, S., Djebbari, H., Boukadida, J., Chaieb, A., Khairi, H. (2007) “Facteurs de risque du portage du streptocoque du groupe B chez la femme enceinte à terme: étude prospective à propos de 294 cas’’ Gynécologie Obstétrique Fertil. 35, 312–316. https://doi.org/10.1016/j.gyobfe.2007.01.027

• Khan, M. A., Faiz, A., & Ashshi, A. M. (2015) “Maternal colonization of group B streptococcus: prevalence, associated factors and antimicrobial resistance’’ Annals of Saudi medicine, 35(6), 423–427. https://doi.org/10.5144/0256-4947.2015.423

• Kwatra, G., Cunnington, M.C., Merrall, E., Adrian, P.V., Ip, M., Klugman, K.P., Tam, W.H., Madhi, S.A. (2016) “Prevalence of maternal colonisation with group B streptococcus: a systematic review and meta-analysis’’ Lancet Infect. Dis. 16, 1076–1084. https://doi.org/10.1016/S1473-3099(16)30055-X

• Lancefield, R.C. (1933) “A serological differentiation of human and other groups of hemolytic streptococci’’ J. Exp. Med. 57, 571–595.

• Lorquet, S., Melin, P., Minon, J.-M., Carpentier, M., Gerday, C., Rigo, J., Foidart, J.-M. (2005) “Le streptocoque du groupe B en clinique anténatale et en salle de travail : un problème d’attitude systématique’’ Rev. Sage-Femme 4, 178–190. https://doi.org/10.1016/S1637-4088(05)86229-7

• Madrid, L., Seale, A.C., Kohli-Lynch, M., Edmond, K.M., Lawn, J.E., Heath, P.T., Madhi, S.A., Baker, C.J., Bartlett, L., Cutland, C., Gravett, M.G., Ip, M., Le Doare, K., Rubens, C.E., Saha, S.K., Sobanjo-Ter Meulen, A., Vekemans, J., Schrag, S., Infant GBS Disease Investigator Group. (2017) “Infant Group B Streptococcal Disease Incidence and Serotypes Worldwide: Systematic Review and Meta-analyses’’ Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am. 65, S160–S172. https://doi.org/10.1093/cid/cix656

• Mahmoud, M., Yahyaoui, G., Benseddik, N., Saadi, M., Chaara, H., Melhouf, M. (2011) “Dépistage de streptocoque du groupe B au cours du troisième trimestre de grossesse au CHU Hassan II de Fès’’ Revue Tunisienne d’Infectiologie. Vol.5, N 1 : 12-15

• Matani, C., Trezzi, M., Matteini, A., Catalani, Carlotta, Messeri, D., Catalani, Corrado. (2016) “Streptococcus agalactiae: prevalence of antimicrobial resistance in vaginal and rectal swabs in Italian pregnant women’’ Infez. Med. 24, 217–221.

• Morach, M. et al. (2018) ‘‘Population structure and virulence gene profiles of Streptococcus agalactiae collected from different hosts worldwide’’ European Journal of Clinical Microbiology & Infectious Diseases, 37(3), pp. 527–536. doi:10.1007/s10096-017-3146-x.

• Moraleda, C., Benmessaoud, R., Esteban, J., López, Y., Alami, H., Barkat, A., Houssain, T., Kabiri, M., Bezad, R., Chaacho, S., Madrid, L., Vila, J., Muñoz-Almagro, C., Bosch, J., Soto, S.M., Bassat, Q. (2018) ‘‘Prevalence, antimicrobial resistance and serotype distribution of group B streptococcus isolated among pregnant women and newborns in Rabat, Morocco’’ J. Med. Microbiol. 67, 652–661. https://doi.org/10.1099/jmm.0.000720

• American Academy of Pediatrics Committee on Infectious Diseases and Committee on Fetus and Newborn: ‘‘Guidelines for prevention of group B streptococcal (GBS) infection by chemoprophylaxis. Pediatrics’’ (1992); 90(5):775-8. PMID: 1408555.

• Rajagopal, L. (2009) ‘‘Understanding the regulation of Group B Streptococcal virulence factors’’ Future Microbiol. 4, 201. https://doi.org/10.2217/17460913.4.2.201

• Raabe, V.N., Shane, A.L. (2019) ‘‘Group B Streptococcus (Streptococcus agalactiae)’’ Microbiol. Spectr. 7. https://doi.org/10.1128/microbiolspec.GPP3-0007-2018

• Russell, N.J., Seale, A.C., O’Driscoll, M., O’Sullivan, C., Bianchi-Jassir, F., Gonzalez-Guarin, J., Lawn, J.E., Baker, C.J., Bartlett, L., Cutland, C., Gravett, M.G., Heath, P.T., Le Doare, K., Madhi, S.A., Rubens, C.E., Schrag, S., Sobanjo-ter Meulen, A., Vekemans, J., Saha, S.K., Ip, M. (2017) ‘‘Maternal Colonization with Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses’’ Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am. 65, S100–S111. https://doi.org/10.1093/cid/cix658

• Seki, T., Kimura, K., Reid, M.E., Miyazaki, A., Banno, H., Jin, W., Wachino, J., Yamada, K., Arakawa, Y. (2015) ‘‘High isolation rate of MDR group B streptococci with reduced penicillin susceptibility in Japan’’ J. Antimicrob. Chemother. 70, 2725–2728. https://doi.org/10.1093/jac/dkv203

• Sherman, J.M. (1937) ‘‘THE STREPTOCOCCI’’ Bacteriol. Rev. 1, 3–97.

• Six, A., Joubrel, C., Tazi, A., Poyart, C. (2014) ‘‘Infections materno-fœtales à Streptococcus agalactiae’’ Presse Médicale 43, 706–714. https://doi.org/10.1016/j.lpm.2014.04.008

• Stoll, B.J., Schuchat, A. (1998) ‘‘Maternal carriage of group B streptococci in developing countries’’ Pediatr. Infect. Dis. J. 17, 499–503. https://doi.org/10.1097/00006454-199806000-00013

• Vanclaire, J., Battisti, O., Francois, A., Chedid, F., Bertrand, J.M., Langhendries, J.P. (1993) ‘‘Infections par streptocoque B en période néonatale : épidémiologie et prévention’’ Archives française de pédiatrie, Vol 50, 427–433.

• Vinnemeier, C.D., Brust, P., Owusu‐Dabo, E., Sarpong, N., Sarfo, E.Y., Bio, Y., Rolling, T., Dekker, D., Adu‐Sarkodie, Y., Eberhardt, K.A., May, J., Cramer, J.P. (2015) ‘‘Group B Streptococci serotype distribution in pregnant women in Ghana: assessment of potential coverage through future vaccines’’ Trop. Med. Int. Health 20, 1516–1524. https://doi.org/10.1111/tmi.12589

• Wang, P., Tong, J., Ma, X., Song, F., Fan, L., Guo, C., Shi, W., Yu, S., Yao, K., Yang, Y. (2015) ‘‘Serotypes, Antibiotic Susceptibilities, and Multi-Locus Sequence Type Profiles of Streptococcus agalactiae Isolates Circulating in Beijing, China’’ PLOS ONE 10(3): e0120035. https://doi.org/10.1371/journal.pone.0120035

• World Health Organization. (2021) ‘‘WHO news release: -Urgent need for vaccine to prevent deadly Group B streptococcus. Nov 2nd 2021’’. https://www.who.int/fr/news/item/02-11-2021-urgent-need-for-vaccine-to-prevent-deadly-group-b-streptococcus


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