aetiology and outcome of community acquired pneumonia at a tertiary hospital in Lafia Nigeria.
DOI:
https://doi.org/10.34874/PRSM.mjph-vol3iss2.27218Keywords:
aetiology, community acquired pneumonia, outcomeAbstract
Background: Pneumonia is the commonest and the most severe form of the lower respiratory tract infection. With increasing needs and dwindling resources, the knowledge of the burden of disease in an area will be critical to health-care planning, resource mobilization and allocation of same. This study seeks to identify the pathogens responsible for this devastating childhood disease so as to guide choice of anti-microbial and as such preventing the development of resistance and wasteful spending.
Methods: This was a descriptive cross sectional study of children aged < 18 years admitted with the diagnosis of Pneumonia at a tertiary health facility in Lafia North-central Nigeria from the 1st of January to the 31st of December 2019. We obtained relevant data using a standard pre-tested study proforma and analyzed using SPSS v.20.0
Results: Community acquired pneumonia accounted for 11.3% of the overall admissions and most of the children (94.3%) were below age five. Pneumonia accounted for 19.6% of the overall mortality with a case fatality of 15.6%. Blood culture was positive in 33.1% of cases while Klebsiella sp. and Staphylococcus aureus were responsible for two-third (69.8%) of the pathogens isolated. Sensitivities were more to the Quinolones and the Aminoglycosides, while resistances were more to the Penicillin (Ampicillin and Amoxicilin).
Conclusion: Community acquired pneumonia remains a common cause of under five morbidity and mortality with a positive blood culture in a third of cases. Klebsiella sp and Staphylococcus aureus were the leading pathogenic cause of pneumonia in this study. The Quinolones in addition to the aminoglycosides should be considered as the first line antibiotics in management of childhood pneumonia.
References
REFERENCES
Hassen, M. et al. (2019) ‘Radiologic Diagnosis and Hospitalization among Children with Severe Community Acquired Pneumonia : A Prospective Cohort Study’, BioMed Research International, 20, pp. 1–19.
Salih, K. E. M. A. et al. (2011) ‘Original Article Characteristics associated with severe pneumonia in under-five children admitted to emergency units of two teaching hospitals in Khartoum , Sudan’, Sudanese Journal of Paediatrics, 11(2), pp. 25–31.
Shin, E. J. et al. (2018) ‘The changes of prevalence and etiology of pediatric pneumonia from National Emergency Department Information System in Korea, between 2007 and 2014’, Korean J Pediatr, 61(9), pp. 291–300.
Price, B. et al. (2019) ‘Aetiology and risks factors associated with the fatal outcomes of childhood pneumonia among hospitalised children in the Philippines from 2008 to 2016 : a case series study’, BMJ, 9, pp. 1–17. doi: 10.1136/bmjopen-2018-026895.
Gritly, S. M. O. et al. (2018) ‘Risk Factors of Pneumonia Among Children Under 5 Years at a Pediatric Hospital in Sudan’, International Journal of Medical Research & Health Sciences, 7(4), pp. 60–68.
Yiltok, E. S. et al. (2017) ‘Pattern and Trends of Respiratory Disease Admissions at the Emergency Paediatrics Unit of Jos University Teaching Hospital – A Four Year Review’, British Journal of Medicine & Medical Research, 22(December 2015), pp. 1–6. doi: 10.9734/BJMMR/2017/34099.
Nirmolia, N. et al. (2018) ‘Prevalence and risk factors of pneumonia in under five children living in slums of Dibrugarh town’, Clinical Epidemiology and Global Health. INDIACLEN, 6(1), pp. 1–4. doi: 10.1016/j.cegh.2017.07.004.
Ramezani, M., Aemmi, S. Z. and Moghadam, Z. E. (2015) ‘Factors Affecting the Rate of Pediatric Pneumonia in Developing Countries : a Review and Literature Study’, Int J Pediatr, 3(24), pp. 1173–1181.
Olowu, A. et al. (2015) ‘Management of community acquired pneumonia (CAP) in children : Clinical practice guidelines by the Paediatrics Association of Nigeria (PAN)’, Niger J Paed, 42(4), pp. 283–292.
Abdulkarim, A. et al. (2013) ‘Childhood pneumonia at the University of Ilorin Teaching Hospital, Ilorin Nigeria’, Niger J Paed, 40(3), pp. 284–289.
Kuti, B. and Oyelami, O. (2015) ‘Childhood community acquired pneumonia at the Wesley Guild H ospital Ilesha: prevalence, pattern and outcome determinants.’, Niger J Health Sci., 15, pp. 98–104.
Verani, J. R. et al. (2015) ‘Under treatment of pneumonia among children under 5 years of age in a malaria-endemic area: population-based surveillance study conducted in Manhica district- rural, Mozambique’, International Journal of Infectious Diseases, 36, pp. 39–45. doi: 10.1016/j.ijid.2015.05.010.