SYNTHESIS AND SPECTROSCOPIC CHARACTERAZATION OF BISINDOLO[2,3-b]QUINOXALINE DERIVATIVES

Authors

  • Khalil Al Mamari
  • Abdulsalam Alsubari
  • Youssef Kandri Rodi
  • El Mokhtar Essassi

Abstract

7-bis-indolo[2,3-b] quinoxaline derivatives have been synthesized
through the condensation of o-phenylenediamine 4 with 1-long chain alkylindoline-2,3-diones 1-3 in refluxing xylene for 12 hours to lead to the
corresponding 6-alkyl-6(H)-indolo[2,3-b]quinoxalines 5-7. Moreover, the
condensation of 1,2-diaminocyclohexane with isatin derivatives 9-11 in
refluxing methanol in the presence of acetic acid as catalyst affords 1,2,3,4-
tetrahydro-indolo[2,3-b] quinoxalines 12-14.
Finally, the condensation of o-phenylenediamine 4 with 1,4-(butane-1,4-diyl)-
bis-indolin-2-one 16 in refluxing xylene for 24 hours leads to 1,4-bis-(6Hindolo[2,3-b]diyl-quinoxalin-6-yl) butane 17.
The structures of all compounds obtained have been elucidated on the basis on
1H NMR, 13C NMR spectroscopy and mass spectrometry.

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Published

13-03-2024

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