A CONVENIENT SYNTHESIS OF NEW 5-AMINO-4,5-DIHYDRO-1HPYRAZOL-1-YL PROPANE NITRILE AND 4,5-DIHYDRO [2-(CYANOAMINO)] PYRIMIDINES

Authors

  • Mohamed Mohamed Université Mohammed V de Rabat
  • Mohamed Lotfi Efrit
  • Madiha Kamoun

DOI:

https://doi.org/10.48369/IMIST.PRSM/jmch-v19i3.24260

Abstract

An efficient method for the synthesis of 5-amino-4,5-dihydro-1H-pyrazol-1-yl propannitrile derivatives 2 and 4,5-dihydro [2-(cyanoamino)] pyrimidines 3 in good yields by the Treatment of 2-aryllydene malononitriles 1 with dicyanodiamide in n- pentanol or 2- cyanoethyl-hydrazine in methanol respectively. The structure of newly synthesised product was established by spectral data

Author Biography

Mohamed Mohamed, Université Mohammed V de Rabat

 

 

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Published

28-12-2020