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Ethnobotanical use, phytochemical study, and antioxidant activity of Globularia alypum


 
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1. Title Title of document Ethnobotanical use, phytochemical study, and antioxidant activity of Globularia alypum
 
2. Creator Author's name, affiliation, country Yahya EL-Mernissi; faculté des sciences et techniques al-Hoceima; Morocco
 
2. Creator Author's name, affiliation, country Aziz Zouhri; Bioactives and Environmental Health Laboratory, Faculty of Sciences, Moulay Ismail University, Meknes B.P.11201, Morocco
 
2. Creator Author's name, affiliation, country Amina Labhar; Applied chemistry team, Faculty of Sciences and Techniques, Abdelmalek Essaadi University, 32 003 Al Hoceima, Morocco; Morocco
 
2. Creator Author's name, affiliation, country Ikrame Zeouk; Laboratory of Pharmaceutical Industry, National Agency of Medicinal and Aromatic Plants, Taounate 34025, Morocco; Morocco
 
2. Creator Author's name, affiliation, country M’hamed Ahari; Applied chemistry team, Faculty of Sciences and Techniques, Abdelmalek Essaadi University, 32 003 Al Hoceima, Morocco; Morocco
 
2. Creator Author's name, affiliation, country Amin Salhi; Applied chemistry team, Faculty of Sciences and Techniques, Abdelmalek Essaadi University, 32 003 Al Hoceima, Morocco; Morocco
 
2. Creator Author's name, affiliation, country Soufian El Barkany; Laboratory of molecular chemistry, Materials and Environement (LMCME) Departement of Chemistry Faculty multidisciplinary Nador, Mohamed 1st University, P .B 300, Nador 62700, Morocco; Morocco
 
2. Creator Author's name, affiliation, country Lhoussain Hajji; Bioactives and Environmental Health Laboratory, Faculty of Sciences, Moulay Ismail University, Meknes B.P.11201, Morocco
 
2. Creator Author's name, affiliation, country Hassan Amhamdi; Applied chemistry team, Faculty of Sciences and Techniques, Abdelmalek Essaadi University, 32 003 Al Hoceima, Morocco; Morocco
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Antioxidant activity, DPPH, Phytochemical analysis, Globularia alypum
 
4. Description Abstract

This work aimed to highlight the biological effects of Globularia alypum L., a medicinal plant widely used in phytotherapy.

Globularia alypum L. is a plant used in traditional medicine in Morocco, the crude extracts prepared from the leaves were obtained using maceration in methanol, ethyl acetate, butanol, and water. The content of total polyphenols was determined using the Folin-Ciocalteu reagent, the first range was for the ethyl acetate extract, followed by butanol, methanol, and aqueous extracts, respectively. The flavonoids amount was determined using the aluminum chloride colorimetric method, the methanolic extract presented the highest content of flavonoids, followed by the one of butanol, then the ethyl acetate and aqueous extracts. The antioxidant activity was carried out using the anti-free radical method based on 2,2-diphenyl-1-picrylhydrazyle (DPPH), the IC50 values were estimated for methanolic, ethyl acetate, butanol and aqueous extracts while that of BHT and ascorbic acid. The high phenolic and flavonoid amounts as well as the antioxidant potential of the extracts indicated that the G. alypum could be exploited as a source of natural antioxidants.

 
5. Publisher Organizing agency, location
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 20-05-2023
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://revues.imist.ma/index.php/AJMAP/article/view/30065
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.48347/IMIST.PRSM/ajmap-v9i1.30065
 
11. Source Title; vol., no. (year) Arabian Journal of Medicinal and Aromatic Plants; Vol 9, No 1 (2023)
 
12. Language English=en en
 
13. Relation Supp. Files Author contributions and Certificate of Submission (13KB)
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2023 Arabian Journal of Medicinal and Aromatic Plants
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