The evaluation of antibacterial and antiproliferative activities of Rosmarinus officinalis essential oil from southern Morocco
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | The evaluation of antibacterial and antiproliferative activities of Rosmarinus officinalis essential oil from southern Morocco |
| 2. | Creator | Author's name, affiliation, country | Mounia Cherki; Hassan II University; Morocco |
| 2. | Creator | Author's name, affiliation, country | Mounchid Karima; Hassan II University; Morocco |
| 2. | Creator | Author's name, affiliation, country | Dersi Noureddine; Institut Pasteur; Morocco |
| 2. | Creator | Author's name, affiliation, country | Habti Noreddine; Hassan II University; Morocco |
| 2. | Creator | Author's name, affiliation, country | Alaoui Ismaili Mustapha; Hassan II Agronomic and Veterinary Institute.; Morocco |
| 2. | Creator | Author's name, affiliation, country | Aboussaouira Touria; University Hassan II; Morocco |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | antibacterial activity, antiproliferative activity, essential oil, Rosmarinus officinalis. |
| 4. | Description | Abstract | Essential oils of plants contain many bioactive molecules and have recently a considerable place of application in pharmaceutical, cosmetic and food industry. The aim of this work is to study antibacterial and antiproliferative activities of Rosmarinus officinalis essential oil. Essential oil was extracted from dried plant by hydrodistillation, and then analyzed by gas chromatography-mass spectrometry (GC/MS). The antibacterial activity of the essential oil was tested by micro-atmosphere technique and agar diffusion against seven strains bacteria. The antiproliferative activity was determined by viability test against P3X63Ag8 myeloma cell in presence of various amount of essential oil. The morphological alterations were searched after staining of treated cells by le May-Grünwald-Giemsa. Our results showed that the major component detected in R. officinalis essential oil is 1.8-cineole (42%). This essential oil revealed an important antibacterial activity against resistant bacteria. The viability test showed a cytotoxic effect of essential oil on P3X63Ag8 myeloma cell. The morphological of the treated tumor cells analysis revealed a cellular lysis with membrane rupture, a hypertrophy and chromatin condensation. In conclusion, the R. officinalis essential oil could have an antibacterial activity against resistant bacteria and antiprolioferative activity against myeloma cells. |
| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (YYYY-MM-DD) | 02-08-2022 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://revues.imist.ma/index.php/AJMAP/article/view/28716 |
| 10. | Identifier | Digital Object Identifier (DOI) | https://doi.org/10.48347/IMIST.PRSM/ajmap-v8i2.28716 |
| 11. | Source | Title; vol., no. (year) | Arabian Journal of Medicinal and Aromatic Plants; Vol 8, No 2 (2022) |
| 12. | Language | English=en | en |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
Copyright (c) 2022 Arabian Journal of Medicinal and Aromatic Plants This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |