Ethnobotanical Appraisal and In-silico Investigation of Plants Used for the Management of COVID-19 in Southwestern Nigeria
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Ethnobotanical Appraisal and In-silico Investigation of Plants Used for the Management of COVID-19 in Southwestern Nigeria |
| 2. | Creator | Author's name, affiliation, country | Ogunyemi Olajide Oderinlo; Department of Chemistry, Federal University Otuoke, Bayelsa; Nigeria |
| 2. | Creator | Author's name, affiliation, country | Olapeju Aderinola Adenekan; National Centre for Technology Management, Lagos; Nigeria |
| 2. | Creator | Author's name, affiliation, country | Taye Temitope Alawode; Department of Chemistry, Federal University Otuoke, Bayelsa; Nigeria |
| 2. | Creator | Author's name, affiliation, country | Paul Matthew Osamudiamen; Department of Chemical Sciences, Bells University of Technology, Ota; Nigeria |
| 2. | Creator | Author's name, affiliation, country | Bolaji Bosede Oluremi; Department of Pharmaceutical Microbiology, University of Ibadan, Ibadan; Nigeria |
| 2. | Creator | Author's name, affiliation, country | Oluwatoba Emmanuel Oyeneyin; Department of Chemical Sciences, Adekunle Ajasin University, Akungba-Akoko; Nigeria |
| 2. | Creator | Author's name, affiliation, country | Mpho Phehello Ngoepe; Department of Oral Biology, University of the Witwatersrand, Gauteng; South Africa |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | COVID-19; Herbal Flora; In-silico Docking; Phytochemicals; SARS-CoV-2; Southwestern Nigeria |
| 4. | Description | Abstract | The continued spread of 2019 novel coronavirus disease is a serious threat to global health. Currently, no approved vaccines or antiviral agents for treatment exist, but, there are many anecdotal accounts of the use of herbal concoctions for the management of this disease in many low-income settings, including Nigeria abound. Using a combination of a web-based survey, and face-to-face interviews with local herbal sellers, this study documents the herbal flora used in the management of COVID-19 in Southwestern Nigeria, and also probes their potential as inhibitors of SARS-CoV-2 proteins. The preliminary in-silico studies identified taraxerol, vernonioside D2, nimbolide and mangiferoleanone as potential hit candidates for COVID-19. The current findings highlight that nature can be a source for the discovery of medicinal agents active against COVID-19. These preliminary results necessitate further in-vitro and in-vivo experimental evidence. |
| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (YYYY-MM-DD) | 09-02-2021 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://revues.imist.ma/index.php/AJMAP/article/view/23748 |
| 10. | Identifier | Digital Object Identifier (DOI) | https://doi.org/10.48347/IMIST.PRSM/ajmap-v7i1.23748 |
| 11. | Source | Title; vol., no. (year) | Arabian Journal of Medicinal and Aromatic Plants; Vol 7, No 1 (2021) |
| 12. | Language | English=en | en |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
Copyright (c) 2021 Arabian Journal of Medicinal and Aromatic Plants This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |