Myricetin and its derivatives; potential therapeutic effect on human health: a review

Abstract

Myricetin is the plant-based secondary metabolite belonging to flavonoids, a class of natural products. It is a simple structure, ubiquitously present in various fruits, vegetables and beverages. It is the oldest flavanols discovered with a polyphenolic structure as a yellow dye from the bark of Myrica nagi Thunb. also known as Myrica esculenta Buch.-Ham. ex D. Don (Myricaceae). Myricetin and its derivatives play multiple biological functions and crucial roles in the prevention, treatment and management of human diseases. This review explored the sources of myricetin, its chemical structure, extraction, isolations, characterizations, biological activities and therapeutic effect of myricetin and its derivatives on human health.