Determination of Sennosides A and B in Sudanese Medicinal Plant Senna alexandrina Pods and Leaves using Reverse-Phase High Performance Liquid Chromatography

Mohammed B Suliman, Awatif A Mohammed


Senna alexandrina pods and leaves have been used in herbal medicine since ancient times. The extracts of this plant contain mainly anthraquinone glycosides that have a significant laxative effect. In this study, the sennosides A and B, the major constituents of Senna alexandrina were calculated via a simple and accurate HPLC method. The yield of sennoside A was found 1.22 and 1.83% in the pods and leaves, respectively. Whereas the yield of sennoside B was found 2.7 and 1.83% in the pods and leaves, respectively.


Senna alexandrina; anthraquinone glycosides; sennosides; laxative effect

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Copyright (c) 2019 Arabian Journal of Medicinal and Aromatic Plants

ISSN: 2458-5920