THE THEORETICAL EVALUATION OF CoO(OH)-ASSISTED METFORMIN ELECTROCHEMICAL DETECTION IN ALKALINE MEDIA

Authors

  • Volodymyr Valentynovych Tkach Chernivtsi National University
  • Marta V. Kushnir 1, 3, 3,2, ,1, , 5, 5,4 5
  • Yana G. Ivanushko
  • Anzhelika F. Molodianu
  • Sílvio C. de Oliveira
  • Petro I. Yagodynets´
  • Zholt O. Kormosh
  • Olga V. Luganska
  • Vira V. Kopiika
  • Nataliia V. Novosad

DOI:

https://doi.org/10.48422/IMIST.PRSM/ajees-v6i4.22453

Keywords:

drug safety, metformin, chemically modified electrodes, cobalt(III) oxyhydroxide, electrochemical detection, stable steady-state

Abstract

The metformin electrochemical detection, assisted by cobalt (III) oxyhydroxide has been evaluated from the theoretical point of view. The correspondent mathematical model has been developed and analyzed by means of linear stability theory and bifurcation analysis. It was shown that CoO(OH) may be applied as an efficient electrode modifier in the detection of metformin in neutral and lightly alkaline media. The electrochemical response has to be clear and easy to interpret. The possibility of the oscillatory and monotonic instabilities has also been verified.

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Published

31-12-2020

Issue

Vol. 6 No. 4 (2020)

Section

Articles